Evaluation of Androgen Levels in Patients with Acute Coronary Syndrome

Abstract

Objectives: To determine plasma levels of free Testosterone (fT) and dehydroepiandrosterone sulphate (DHEA-S) in male patients with acute coronary syndrome. Methods: We checked the serum fT and DHEA-S levels of 30 healty male subjects and 64 male patients with acute coronary syndrome whose coronary artery diseases were confirmed by coronary angiography. Results: We observed no difference between two groups on the level of fT while DHEA-S level was significantly lower (p = 0.01). No correlation had existed between lipid parameters and levels of fT and DHEA-S. Conclusion: More comprehensive studies are needed about whether lower levels of DHEAS in patients are contributed to acute coronary syndrome or are the effect of disease. [Med-Science 2012; 1(4.000): 323-30]

Keywords

• free testosterone
• dehydroepiandrosterone sulphate
• acute coronary syndrome
• coronary artery disease