Clinical Ophthalmology (Aug 2023)
Spotlight on Lattice Degeneration Imaging Techniques
Abstract
Dmitrii S Maltsev,1 Alexei N Kulikov,1 Venera A Shaimova,2,3 Maria A Burnasheva,1 Alexander S Vasiliev1 1Department of Ophthalmology, Military Medical Academy, St. Petersburg, Russia; 2Academy of Postgraduate Education of the Federal Scientific and Clinical Center of Specialized Medical Care and Medical Technologies, Moscow, Russia; 3“Center Zreniya”, Chelyabinsk, RussiaCorrespondence: Dmitrii S Maltsev, Department of Ophthalmology, Military Medical Academy, 21, Botkinskaya Street, St. Petersburg, 194044, Russia, Email [email protected]: Lattice degeneration (LD), routinely diagnosed with indirect ophthalmoscopy, is one of the most common and clinically significant peripheral retinal findings. In this review, we have summarized the data on currently available imaging techniques which help to improve diagnosis and our understanding of LD pathogenesis. Ultra-wide field imaging provides reliable color fundus capturing for the primary diagnosis of LD and may also be used as a screening tool. Wide-field imaging can be used for targeted documentation of LD lesions using true colors and with minimal optical distortions. Information on the status of the vitreoretinal interface, including detection of retinal holes, detachments, and vitreous tractions, can be obtained with peripheral structural optical coherence tomography (OCT) or scanning laser ophthalmoscopy in retro-mode. These techniques clarify the associated risks of rhegmatogenous retinal detachment. Fundus autofluorescence can provide details on atrophic changes. However, the risk of retinal detachment by means of this technique requires further investigation. OCT angiography may be successfully performed for some lesions. Taken together, OCT and OCT angiography demonstrate thinning of the choroid, alteration of local choroidal microcirculation, and, in severe lesions, involvement of the sclera. OCT angiography confirms loss of retinal microcirculation within LD lesion, which was previously shown with fluorescein angiography. In conclusion, despite relatively simple primary diagnosis, imaging of LD lesions remains challenging due to their peripheral localization. However, several new strategies, including ultra-wide field imaging, peripheral OCT, and scanning laser ophthalmoscopy, make LD imaging possible on a routine basis, improving diagnosis and understanding of LD pathogenesis.Keywords: lattice degeneration, ultra-wide field imaging, scanning laser ophthalmoscopy, optical coherence tomography angiography, optical coherence tomography, choroid, peripheral retinal degeneration, multimodal imaging, retinal detachment
