Case Reports in Oncology (Feb 2017)

T-Cell Lymphoma in a Patient with Neurofibromatosis Type 1 and AIDS

  • Izana Junqueira de Castro,
  • Esther Botelho Soares da Silva,
  • Talita Rezende dos Santos,
  • Amanda Barroso de Freitas,
  • Inara Junqueira de Castro,
  • Alessandra Santos Portela,
  • Marilza Campos de Magalhães,
  • Karina Lebeis Pires,
  • Guilherme Almeida Rosa da Silva,
  • Marcelo Costa Velho Mendes de Azevedo

DOI
https://doi.org/10.1159/000456029
Journal volume & issue
Vol. 10, no. 1
pp. 161 – 168

Abstract

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Neurofibromatosis type 1 (NF1) and AIDS are risk factors for the development of malignant neoplasms, including hematological malignancies, such as non-Hodgkin lymphoma. NF1 is an autosomal dominant disease that primarily manifests as café-au-lait spots, dermal neurofibromas, axillary and/or inguinal ephelides or freckles, plexiform neurofibromas, Lisch nodules, and bone deformities. In this report, we present a 38-year-old female patient with NF1 from childhood and AIDS who developed peripheral T-cell lymphoma with good response to chemotherapeutic treatment.

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