Ethyl 4-hydroxy-1-(2-morpholinopropanoyl)-2,6-diphenyl-1,2,5,6-tetrahydropyridin-3-carboxylate

Abstract

In the title compound, C27H32N2O5, the morpholine ring adopts a chair conformation with two C atoms deviating by −0.656 (4) and 0.679 (3) Å from the least-squares plane defined by the rest of atoms in the ring. The tetrahydropyridine ring adopts a half-chair conformation. The molecular structure is stabilized by a strong intramolecular O—H...O interaction, generating an S(6) motif. The crystal packing is stabilized by intermolecular C—H...O interactions, generating a C(7) chain along the a axis, and R22(20) and R44(20) graph-set motifs.