Annals of Internal Medicine: Clinical Cases (Jul 2024)

Cytomegalovirus-Related Immune Thrombocytopenic Purpura in an Immunocompetent Adult

  • Derek J. Essegian,
  • Rachel A. Sibley

DOI
https://doi.org/10.7326/aimcc.2023.1089
Journal volume & issue
Vol. 3, no. 7

Abstract

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We present the case of a 42-year-old immunocompetent man who was diagnosed with acute immune thrombocytopenic purpura and had evidence of an acute cytomegalovirus infection, concerning for secondary immune thrombocytopenic purpura. The patient presented with diffuse petechial rash, epistaxis, and gingival bleeding after a prodromal flu-like illness. His initial laboratory test results were significant for transaminitis, a platelet count of 6 K/μL, and a cytomegalovirus viral load of 2030 copies. He was treated with dexamethasone, intravenous immunoglobulin, and valganciclovir, with improvement noted in his platelet count to 331 K/μL.