Brazilian Propolis Intake Decreases Body Fat Mass and Oxidative Stress in Community-Dwelling Elderly Females: A Randomized Placebo-Controlled Trial

Miho Kanazashi; Tadayuki Iida; Ryosuke Nakanishi; Masayuki Tanaka; Hiromi Ikeda; Naomi Takamiya; Noriaki Maeshige; Hiroyo Kondo; Tomohiko Nishigami; Toshihide Harada; Hidemi Fujino

doi:10.3390/nu15020364

Nutrients (Jan 2023)

Brazilian Propolis Intake Decreases Body Fat Mass and Oxidative Stress in Community-Dwelling Elderly Females: A Randomized Placebo-Controlled Trial

Miho Kanazashi,
Tadayuki Iida,
Ryosuke Nakanishi,
Masayuki Tanaka,
Hiromi Ikeda,
Naomi Takamiya,
Noriaki Maeshige,
Hiroyo Kondo,
Tomohiko Nishigami,
Toshihide Harada,
Hidemi Fujino

Affiliations

Miho Kanazashi: Department of Physical Therapy, Faculty of Health and Welfare, Prefectural University of Hiroshima, Mihara 723-0053, Japan
Tadayuki Iida: Department of Physical Therapy, Faculty of Health and Welfare, Prefectural University of Hiroshima, Mihara 723-0053, Japan
Ryosuke Nakanishi: Department of Physical Therapy, Faculty of Rehabilitation, Kobe International University, Kobe 658-0032, Japan
Masayuki Tanaka: Department of Physical Therapy, Faculty of Health Sciences, Okayama Healthcare Professional University, Okayama 700-0913, Japan
Hiromi Ikeda: Department of Physical Therapy, Faculty of Health and Welfare, Prefectural University of Hiroshima, Mihara 723-0053, Japan
Naomi Takamiya: Department of Physical Therapy, Faculty of Health and Welfare, Prefectural University of Hiroshima, Mihara 723-0053, Japan
Noriaki Maeshige: Department of Rehabilitation Science, Kobe University Graduate School of Health Sciences, Kobe 654-0142, Japan
Hiroyo Kondo: Department of Food Science and Nutrition, Nagoya Women’s University, Nagoya 467-8611, Japan
Tomohiko Nishigami: Department of Physical Therapy, Faculty of Health and Welfare, Prefectural University of Hiroshima, Mihara 723-0053, Japan
Toshihide Harada: Department of Physical Therapy, Faculty of Health and Welfare, Prefectural University of Hiroshima, Mihara 723-0053, Japan
Hidemi Fujino: Department of Rehabilitation Science, Kobe University Graduate School of Health Sciences, Kobe 654-0142, Japan

DOI: https://doi.org/10.3390/nu15020364
Journal volume & issue: Vol. 15, no. 2
p. 364

Abstract

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This study aimed to investigate the effects of Brazilian propolis on body fat mass and levels of adiponectin and reactive oxygen species among community-dwelling elderly females. This was a double-blind randomized placebo-controlled trial. Altogether, 78 females aged 66–84 years were randomly assigned to the propolis (PRO; n = 39) or placebo (PLA; n = 39) group. For 12 weeks, the PRO group were given three capsules containing 227 mg of propolis twice a day. Meanwhile, the PLA group were given daily placebo capsules. Of 78 participants, 53 (PLA group: n = 28, PRO group: n = 25) completed the study. Although no changes were observed in absolute or relative fat mass in the PLA group, they showed a significant decline in the PRO group. The level of serum adiponectin in the PLA group did not change, although that of the PRO group significantly increased. The level of d-ROMs in the PLA group significantly increased, whereas that of the PRO group significantly decreased. The serum SOD activity in the PLA group significantly decreased, whereas that of the PRO group tended to increase. These results suggest that propolis supplementation may decrease body fat mass and oxidative stress among community-dwelling elderly females.

Published in Nutrients

ISSN: 2072-6643 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Technology: Home economics: Nutrition. Foods and food supply
Website: https://www.mdpi.com/journal/nutrients

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