Pre-diagnostic trajectories of lymphocytosis predict time to treatment and death in patients with chronic lymphocytic leukemia

Michael Asger Andersen; Mia Klinten Grand; Christian Brieghel; Volkert Siersma; Christen Lykkegaard Andersen; Carsten Utoft Niemann

doi:10.1038/s43856-022-00117-4

Communications Medicine (May 2022)

Pre-diagnostic trajectories of lymphocytosis predict time to treatment and death in patients with chronic lymphocytic leukemia

Michael Asger Andersen,
Mia Klinten Grand,
Christian Brieghel,
Volkert Siersma,
Christen Lykkegaard Andersen,
Carsten Utoft Niemann

Affiliations

Michael Asger Andersen: Department of Hematology, Rigshospitalet, Copenhagen University Hospital
Mia Klinten Grand: The Research Unit for General Practice and Section of General Practice, Department of Public Health, University of Copenhagen
Christian Brieghel: Department of Hematology, Rigshospitalet, Copenhagen University Hospital
Volkert Siersma: The Research Unit for General Practice and Section of General Practice, Department of Public Health, University of Copenhagen
Christen Lykkegaard Andersen: Department of Hematology, Rigshospitalet, Copenhagen University Hospital
Carsten Utoft Niemann: Department of Hematology, Rigshospitalet, Copenhagen University Hospital

DOI: https://doi.org/10.1038/s43856-022-00117-4
Journal volume & issue: Vol. 2, no. 1
pp. 1 – 8

Abstract

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Andersen et al. evaluate lymphocyte dynamics in chronic lymphocytic leukemia (CLL) patients prior to diagnosis. The authors develop a model to predict risk of requiring CLL treatment or death based on pre-diagnostic lymphocyte growth rates.

Published in Communications Medicine

ISSN: 2730-664X (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Medicine
Website: https://www.nature.com/commsmed/

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