An Actual Approach to the Problem of Cough in Acute Respiratory Infections in Children

Abstract

This article presents the results of experimental and clinical studies of the release active combined drug having anti-tussive, antiinflammatory and bronchodilatory effects. The mechanism of action of this drug is implemented through the regulatory (modifying) effect on bradykinin, histamine, and opiate receptors, which are directly involved in central and peripheral units of the cough formation. This feature of the drug action allows to solve different therapeutic problems in the treatment of patients with dry/non-productive and wet/productive cough during the whole period of the disease. The review also presents clinical evidence of efficacy and safety of the reviewed drug in the treatment of productive and non-productive cough at ARI in children at any stage of infectious-inflammatory process. The review of literature allows to conclude that the combined composition of the discussed anti-tussive drug providing its comprehensive effect, helps to prevent polypharmacy, minimizing the drug load on a child's body.

Keywords

• cough
• effective therapy
• acute respiratory infection