Characteristics of proton pump inhibitor‐resistant severe reflux esophagitis and efficacy of vonoprazan in elderly (older than 75 years) and non‐elderly groups

Abstract

Abstract Background and Aim Previous studies on age differences in proton pump inhibitor (PPI)‐resistant reflux esophagitis (RE) have found that stenosis and bleeding complications were significantly more common in the elderly than in the non‐elderly. We sought to examine differences between two groups of elderly (75 years or older) and non‐elderly (4 cm) was significantly higher in the elderly group, while significantly more non‐elderly patients had collagen disease. In the non‐elderly group with scleroderma, the efficacy of VPZ 20 mg may not be sufficient.

Keywords

• elderly
• proton pump inhibitor‐resistant severe reflux esophagitis
• saliva
• vonoprazan