Neuroplasticity and Exercise Study Group (Grupo de Estudos em Neuroplasticidade e Exercício – GENE), UFVJM, Diamantina, MG, Brazil; Multicenter Post Graduation Program in Physiological Sciences (PMPGCF), UFVJM, Brazilian Society of Physiology, Diamantina, MG, Brazil
Carina de Sousa Santos
Multicenter Post Graduation Program in Physiological Sciences (PMPGCF), UFVJM, Brazilian Society of Physiology, Diamantina, MG, Brazil
Caíque Olegário Diniz e Magalhães
Neuroplasticity and Exercise Study Group (Grupo de Estudos em Neuroplasticidade e Exercício – GENE), UFVJM, Diamantina, MG, Brazil; Multicenter Post Graduation Program in Physiological Sciences (PMPGCF), UFVJM, Brazilian Society of Physiology, Diamantina, MG, Brazil
Lucas Renan Sena de Oliveira
Neuroplasticity and Exercise Study Group (Grupo de Estudos em Neuroplasticidade e Exercício – GENE), UFVJM, Diamantina, MG, Brazil; Multicenter Post Graduation Program in Physiological Sciences (PMPGCF), UFVJM, Brazilian Society of Physiology, Diamantina, MG, Brazil
Marco Fabrício Dias Peixoto
Department of Physical Education, Federal University of the Valleys of Jequitinhonha and Mucuri (UFVJM), Diamantina, MG, Brazil; Neuroplasticity and Exercise Study Group (Grupo de Estudos em Neuroplasticidade e Exercício – GENE), UFVJM, Diamantina, MG, Brazil; Multicenter Post Graduation Program in Physiological Sciences (PMPGCF), UFVJM, Brazilian Society of Physiology, Diamantina, MG, Brazil; Post Graduation Program in Health Science (PPGCS), UFVJM, Diamantina, MG, Brazil
Ricardo Augusto Leoni De Sousa
Neuroplasticity and Exercise Study Group (Grupo de Estudos em Neuroplasticidade e Exercício – GENE), UFVJM, Diamantina, MG, Brazil; Multicenter Post Graduation Program in Physiological Sciences (PMPGCF), UFVJM, Brazilian Society of Physiology, Diamantina, MG, Brazil
Ricardo Cardoso Cassilhas
Department of Physical Education, Federal University of the Valleys of Jequitinhonha and Mucuri (UFVJM), Diamantina, MG, Brazil; Neuroplasticity and Exercise Study Group (Grupo de Estudos em Neuroplasticidade e Exercício – GENE), UFVJM, Diamantina, MG, Brazil; Multicenter Post Graduation Program in Physiological Sciences (PMPGCF), UFVJM, Brazilian Society of Physiology, Diamantina, MG, Brazil; Post Graduation Program in Health Science (PPGCS), UFVJM, Diamantina, MG, Brazil; Correspondent author at: Rodovia MGT 367 - Km 583, nº 5000, Departamento de Educação Física, Bairro Alto da Jacuba. CEP 39100-000, Diamantina, MG, Brazil.
Calorie restriction (CR) has been considered the most effective non-pharmacological intervention to counteract aging-related diseases and improve longevity. This intervention has shown beneficial effects in the prevention and treatment of several chronic diseases and functional declines related to aging, such as Parkinson's, Alzheimer's, and neuroendocrine disorders. However, the effects of CR on cognition show controversial results since its effects vary according to intensity, duration, and the period of CR. This review focuses on the main studies published in the last ten years regarding the consequences of CR on cognition in different neurological diseases and conditions of experimental animals. Also, possible CR mimetics are discussed. These findings highlight the potential beneficial effects of CR of up to 40 % on cognition when started early in life in non human animals.
