mBio (Apr 2021)

Species-Specific Deamidation of RIG-I Reveals Collaborative Action between Viral and Cellular Deamidases in HSV-1 Lytic Replication

  • Huichao Huang,
  • Jun Zhao,
  • Ting-Yu Wang,
  • Shu Zhang,
  • Yuzheng Zhou,
  • Youliang Rao,
  • Chao Qin,
  • Yongzhen Liu,
  • Yongheng Chen,
  • Zanxian Xia,
  • Pinghui Feng

DOI
https://doi.org/10.1128/mBio.00115-21
Journal volume & issue
Vol. 12, no. 2

Abstract

Read online

Herpesviruses are ubiquitous pathogens in human and establish lifelong persistence despite host immunity. The ability to evade host immune response is pivotal for viral persistence and pathogenesis.