The effect of oral clindamycin and rifampicin combination therapy in patients with hidradenitis suppurativa in Singapore

Abstract

Harumi Ochi, Lixian Chris Tan, Hazel H Oon Department of Dermatology, National Skin Centre, Singapore Abstract: Hidradenitis suppurativa (HS) is a chronic inflammatory disease of follicular occlusion characterized by abscesses, draining sinuses, and scarring. The efficacy and tolerability of combination treatment with oral clindamycin and rifampicin have previously been assessed in 4 studies including groups of Caucasian patients. Overall results are promising with reported improvement rates between 71.4% and 85.7%. In this study, we propose that combination therapy is safe and efficacious in the treatment of HS, not only among Caucasians, but also in a group of Asian patients in Singapore. Keywords: hidradenitis suppurativa, combination therapy, clindamycin, rifampicin

Keywords

• hidradenitis suppurativa
• combination therapy
• clindamycin
• rifampicin