Cellular taxonomy of Hic1+ mesenchymal progenitor derivatives in the limb: from embryo to adult

Martin Arostegui; R. Wilder Scott; Kerstin Böse; T. Michael Underhill

doi:10.1038/s41467-022-32695-1

Nature Communications (Aug 2022)

Cellular taxonomy of Hic1+ mesenchymal progenitor derivatives in the limb: from embryo to adult

Martin Arostegui,
R. Wilder Scott,
Kerstin Böse,
T. Michael Underhill

Affiliations

Martin Arostegui: Biomedical Research Centre, University of British Columbia
R. Wilder Scott: Biomedical Research Centre, University of British Columbia
Kerstin Böse: Biomedical Research Centre, University of British Columbia
T. Michael Underhill: Biomedical Research Centre, University of British Columbia

DOI: https://doi.org/10.1038/s41467-022-32695-1
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 20

Abstract

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Mesenchymal progenitors (MPs) are fundamental to tissue development and regeneration, however, their embryonic origin is unclear. Single cell-omics coupled with lineage tracing reveal a unique somite-derived MP hierarchy in limb morphogenesis.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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