Molecules (Jul 2004)

Isolation and X-ray Crystal Structure of Tetrahydroisoquinoline Alkaloids from Calycotome Villosa Subsp. intermedias

  • Mohammed Lachkar,
  • Brahim El Bali,
  • Michael Bolte,
  • Rachid El Alami,
  • Mohamed Bouktaib,
  • Ibtissam Messouri,
  • Ali El Antri

DOI
https://doi.org/10.3390/90800650
Journal volume & issue
Vol. 9, no. 8
pp. 650 – 657

Abstract

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Two tetrahydroisoquinoline alkaloids were extracted from the alkaloid fraction of a methanol extract of the seeds of Calycotome Villosa Subsp. intermedia. Their structures were established as (R)-1-hydroxymethyl-7-8-dimethoxy-1,2,3,4-tetrahydro- isoquinoline (1) and (S)-7-hydroxymethyl-2-3-dimethoxy-7,8,9,10-tetrahydroisoquinoline chloride (2) by spectroscopic techniques and X-ray diffraction analysis.

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