Immune Thrombocytopenia and JAK2V617F Positive Essential Thrombocythemia: Literature Review and Case Report

M. A. Sobas; T. Wróbel; K. Zduniak; M. Podolak-Dawidziak; J. Rybka; M. Biedroń; M. Sawicki; J. Dybko; K. Kuliczkowski

doi:10.1155/2017/3725089

Case Reports in Hematology (Jan 2017)

Immune Thrombocytopenia and JAK2V617F Positive Essential Thrombocythemia: Literature Review and Case Report

M. A. Sobas,
T. Wróbel,
K. Zduniak,
M. Podolak-Dawidziak,
J. Rybka,
M. Biedroń,
M. Sawicki,
J. Dybko,
K. Kuliczkowski

Affiliations

M. A. Sobas: Department of Haematology, Blood Neoplasms and Bone Marrow Transplantation, Medical University of Wrocław, Wrocław, Poland
T. Wróbel: Department of Haematology, Blood Neoplasms and Bone Marrow Transplantation, Medical University of Wrocław, Wrocław, Poland
K. Zduniak: Department of Pathology, Medical University of Wrocław, Wrocław, Poland
M. Podolak-Dawidziak: Department of Haematology, Blood Neoplasms and Bone Marrow Transplantation, Medical University of Wrocław, Wrocław, Poland
J. Rybka: Department of Haematology, Blood Neoplasms and Bone Marrow Transplantation, Medical University of Wrocław, Wrocław, Poland
M. Biedroń: Department of Haematology, Blood Neoplasms and Bone Marrow Transplantation, Medical University of Wrocław, Wrocław, Poland
M. Sawicki: Department of Haematology, Blood Neoplasms and Bone Marrow Transplantation, Medical University of Wrocław, Wrocław, Poland
J. Dybko: Department of Haematology, Blood Neoplasms and Bone Marrow Transplantation, Medical University of Wrocław, Wrocław, Poland
K. Kuliczkowski: Department of Haematology, Blood Neoplasms and Bone Marrow Transplantation, Medical University of Wrocław, Wrocław, Poland

DOI: https://doi.org/10.1155/2017/3725089
Journal volume & issue: Vol. 2017

Abstract

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We present the case where immune thrombocytopenia (ITP) and essential thrombocythemia (ET) sequentially appeared in the space of twenty-one years of follow-up. Impaired platelet production is present in both diseases, but clinical presentation and treatment are different. On the basis of this case history a possible role of autoimmunity as a predisposing factor to myeloproliferation has been discussed.

Published in Case Reports in Hematology

ISSN: 2090-6560 (Print); 2090-6579 (Online)
Publisher: Hindawi Limited
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the blood and blood-forming organs
Website: https://onlinelibrary.wiley.com/journal/3191

About the journal