Journal of Investigative Medicine High Impact Case Reports (Mar 2020)

A Rare Case of Fungal Burn Wound Infection Caused by in Vietnam

  • Que Anh Tram MD,
  • Nguyen Thai Ngoc Minh MD,
  • Do Ngoc Anh MD,
  • Nguyen Nhu Lam MD,
  • Tran Ngoc Dung MD,
  • Ngo Thi Minh Chau MD,
  • Le Tran-Anh MD

DOI
https://doi.org/10.1177/2324709620912122
Journal volume & issue
Vol. 8

Abstract

Read online

A patient with extensive burn injuries was admitted to the National Hospital of Burns in Hanoi, Vietnam, and diagnosed with fungal wound infection by histological examination of skin biopsy samples. Fusarium solani was isolated and identified by analysis of its morphological features and the sequence of the internal transcribed spacer region. The isolation showed in vitro resistant to fluconazole, voriconazole, itraconazole, amphotericin B, and caspofungin. Invasive fusariosis is difficult to treat due to its angioinvasive property and its lacking amenability to treatment with antifungal drugs. This infection is rare and has not been reported so far in Vietnam.