Nature Communications (Jul 2018)

Intravital imaging-based analysis tools for vessel identification and assessment of concurrent dynamic vascular events

  • Naoki Honkura,
  • Mark Richards,
  • Bàrbara Laviña,
  • Miguel Sáinz-Jaspeado,
  • Christer Betsholtz,
  • Lena Claesson-Welsh

DOI
https://doi.org/10.1038/s41467-018-04929-8
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 10

Abstract

Read online

Different stimuli can induce dynamic changes in blood flow velocity, vessel diameter and permeability. Here the authors develop a multi-photon microscopy-based image analysis tool allowing the identification of vessels and the assessment of rapid changes in large vascular networks.