Clinical, Cosmetic and Investigational Dermatology (Apr 2023)
Scleroderma-Like Lupus Panniculitis: A Case Report and Literature Review
Abstract
Prinpat Pinyowiwat, Suthinee Rutnin, Kumutnart Chanprapaph Division of Dermatology, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, ThailandCorrespondence: Kumutnart Chanprapaph, Division of Dermatology, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, 270 Rama IV Road, Ratchatewi, Bangkok, 10400, Thailand, Tel +662-201-1141, Fax +662-201-1211, Email [email protected]: Sclerodermic or scleroderma-like lupus erythematosus panniculitis (SLEP) shares both clinical and histopathological features between lupus panniculitis and localized scleroderma. It is exceedingly rare. We herein report a case of SLEP manifested with a solitary, firm-to-hard, erythematous plaque in an Asian woman. This patient responded well to intralesional corticosteroid and antimalarials. We have reviewed the pathogenesis of fibrosis in patients with chronic cutaneous lupus erythematosus as well as documented cases of SLEP in the literature.Keywords: cutaneous lupus erythematosus, scleroderma-like lupus erythematosus panniculitis, sclerodermic lupus panniculitis, localized scleroderma, lupus profundus, overlap syndrome
