MODERN ISSUES OF ORGANIZING RADIO PHARM PREPARATIONS PRODUCTION BASED ON ⁶⁸GA

Abstract

Functional diagnostics method (scintigraphy), connected with injection of radioactive isotopes with further getting of 2-D image by emitting radiation detection, is widely used in medicine. Scintigraphic visualization of infections and inflammation with ⁶⁸Ga-citrate is powerful diagnostic instrument for patients with inflammation or infection disease. ⁶⁸Ga is short-lived positron emitting radionuclide (half-life time is 67,6 min, positron energy is 2,92 MeV). Such characteristics allowed to get better images of other radiopharmaceuticals with ⁶⁸Ga. Benefits of the drugs, mechanism of mother radionuclide fission is described in the article, as well as equipment for ⁶⁸Ga-citrate synthesis with all the technological processes. Obtained ⁶⁸Ga-citrate is suitable for positron emission tomography diagnostics for infection disease and inflammation detection in clinical practice.

Keywords

• radiopharmaceuticals
• ⁶⁸ga-citrate synthesis unit
• radiochemical synthesis