Mechanism of Action of N‑Acyl and N‑Alkoxy Fosmidomycin Analogs: Mono- and Bisubstrate Inhibition of IspC from Plasmodium falciparum, a Causative Agent of Malaria
Misgina B. Girma,
Haley S. Ball,
Xu Wang,
Robert C. Brothers,
Emily R. Jackson,
Marvin J. Meyers,
Cynthia S. Dowd,
Robin D. Couch
Affiliations
Misgina B. Girma
Department of Chemistry and Biochemistry, George Mason University, Manassas, Virginia, United States
Haley S. Ball
Department of Chemistry and Biochemistry, George Mason University, Manassas, Virginia, United States
Xu Wang
Progenra Inc., Malvern, Pennsylvania, United States
Robert C. Brothers
Department of Chemistry, The George Washington University, Washington, District of Columbia, United States
Emily R. Jackson
Department of Chemistry, The George Washington University, Washington, District of Columbia, United States
Marvin J. Meyers
Department of Chemistry, Saint Louis University, Saint Louis, Missouri, United States
Cynthia S. Dowd
Department of Chemistry, The George Washington University, Washington, District of Columbia, United States
Robin D. Couch
Department of Chemistry and Biochemistry, George Mason University, Manassas, Virginia, United States
