Jornal de Pediatria (Aug 2016)

Prediction equations for spirometry in four- to six-year-old children

  • Danielle Corrêa França,
  • Paulo Augusto Moreira Camargos,
  • Marcus Herbert Jones,
  • Jocimar Avelar Martins,
  • Bruna da Silva Pinto Pinheiro Vieira,
  • Enrico Antônio Colosimo,
  • Karla Morganna Pereira Pinto de Mendonça,
  • Raíssa de Oliveira Borja,
  • Raquel Rodrigues Britto,
  • Verônica Franco Parreira

DOI
https://doi.org/10.1016/j.jped.2015.10.005
Journal volume & issue
Vol. 92, no. 4
pp. 400 – 408

Abstract

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Abstract Objective To generate prediction equations for spirometry in 4- to 6-year-old children. Methods Forced vital capacity, forced expiratory volume in 0.5 s, forced expiratory volume in one second, peak expiratory flow, and forced expiratory flow at 25–75% of the forced vital capacity were assessed in 195 healthy children residing in the town of Sete Lagoas, state of Minas Gerais, Southeastern Brazil. The least mean squares method was used to derive the prediction equations. The level of significance was established as p < 0.05. Results Overall, 85% of the children succeeded in performing the spirometric maneuvers. In the prediction equation, height was the single predictor of the spirometric variables as follows: forced vital capacity = exponential [(−2.255) + (0.022 × height)], forced expiratory volume in 0.5 s = exponential [(−2.288) + (0.019 × height)], forced expiratory volume in one second = exponential [(−2.767) + (0.026 × height)], peak expiratory flow = exponential [(−2.908) + (0.019 × height)], and forced expiratory flow at 25–75% of the forced vital capacity = exponential [(−1.404) + (0.016 × height)]. Neither age nor weight influenced the regression equations. No significant differences in the predicted values for boys and girls were observed. Conclusion The predicted values obtained in the present study are comparable to those reported for preschoolers from both Brazil and other countries.

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