PLoS ONE (Jan 2021)

Right ventricular dysfunction assessed by cardiovascular magnetic resonance is associated with poor outcome in patients undergoing transcatheter mitral valve repair.

  • Maximilian Spieker,
  • Jonathan Marpert,
  • Shazia Afzal,
  • Athanasios Karathanos,
  • Daniel Scheiber,
  • Florian Bönner,
  • Patrick Horn,
  • Malte Kelm,
  • Ralf Westenfeld

DOI
https://doi.org/10.1371/journal.pone.0245637
Journal volume & issue
Vol. 16, no. 1
p. e0245637

Abstract

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AimsTo evaluate whether CMR-derived RV assessment can facilitate risk stratification among patients undergoing transcatheter mitral valve repair (TMVR).BackgroundIn patients undergoing TMVR, only limited data exist regarding the role of RV function. Previous studies assessed the impact of pre-procedural RV dysfunction stating that RV failure may be associated with increased cardiovascular mortality after the procedure.MethodsSixty-one patients underwent CMR, echocardiography and right heart catheterization prior TMVR. All-cause mortality and heart failure hospitalizations were assessed during 2-year follow-up.ResultsAccording to RV ejection fraction (RVEF) ConclusionIn patients undergoing TMVR, pre-existing RV dysfunction and RV dilatation are associated with reduced survival, in progressive additive fashion. The assessment of RV volumes and function by CMR may aid in risk stratification prior TMVR in these high-risk patients.