Tissue modules as a base of theoretical histology

Abstract

The tissue is suggested to consider as a cell network or lattice with modular structure. The tissue module is named histione. The cell lattices describe like spatial organization of tissues and to be considered as a new biological level which was not taken into account before. Here, the formalized theory of the cell lattice in epithelial tissues is set out. These lattices are to be analyzed by the synthesis of tissue structure computer models. These models are to be cut up and then the cuts of the models are to be compared with the real epithelial sections. After this, the model which cuts according to the real epithelial sections, are to be chosen. It was shown that this new approach has good results for the research of spatial organization of tissues. It has also advantages which the traditional reconstruction by the serial sections has not. It was substantiated that the existing paradigm of the histology are to be changed because now it's the cells which are the research object, but it should be the cell lattices. And when this paradigm is changed, the three-dimensional structural histology is to be created.

Keywords

• histione
• cell lattice
• three-dimensional structure
• epithelial tissue