Hemodynamic indicators of doppler test within arteria profunda linguae in patients with combined pathology of mucous membrane of oral cavity and rheumatoid arthritis

Abstract

Objective: The purpose of this study was to investigate hemodynamic in arteria profunda linguae with the help of Doppler ultrasonography in triplex scanning mode in patients with pathology of mucous membrane of oral cavity and combined rheumatoid arthritis. Materials and methods: The study of the state of the tongue`s vascular net with the help of Doppler ultrasonography in triplex scanning mode was conducted. A prospective diagnostic study was performed on 64 patients with glossopathy which was combined with rheumatoid arthritis. 25 generally healthy persons without pathological changes of the mucous membranes of the mouth were included into the control group. Results: In a detailed analysis of the qualitative and quantitative results of Doppler ultrasonography in patients with superficial type of the benign migratory glossitis combined with rheumatoid arthritis the next features were found: on the background of the local changes in blood flow profile there were a significant increase of linear parameters of a blood flow and to a lesser degree volumetric parameters of a blood flow detected on the background of the local changes in blood flow profile compared to control group with statistically significant difference 95-99,9%. Despite increasing of blood flow velocity, vascular resistance and total blood flow resistance were increased. Elastic properties of the vascular wall reduction indicate circulation intensity decrease in arteria profunda linguae system, which is a sighn of chronic inflammatory process. The presence of significant local hemodynamic disorders in arteria profunda linguae system in patients with hyperplastic form of benign migratory glossitis evidenced by a significant decrease in blood flow velocity Vmax (on 24,7%) and its most sensitive parameter ТАМХ (on 18,9%) as well as indicator of blood supply to the organ СО ( on 24,9%). Worse results of doppler test were determined in patients with atrophic glossitis: flattening of peaks of the echographic curve with occurrence of additional phases of systole and diastole, low blood flow speed and the general tendency to an increase of vascular resistance and the resistance of peripheral blood flow as well as reducing of the elastic properties in the vascular wall. However, a significant decrease of the volumetric blood flow speed on 34,4% (р <0,001) is evidence of impaired blood flow in the microvasculature system of the tongue. Conclusion: It was found that character and degree of violations of local hemodynamic in patients with glossopathy which combined with rheumatoid arthritis depends on the type of glossitis and due to functional and structural changes in the vascular system in the benign migratory glossitis and atrophic glossitis and aggravation on the background of rheumatoid arthritis.

Keywords

• ultrasonography
• benign migratory glossitis
• atrophic glossitis
• tongue hemodynamics