NEOADJUVANT THERMOCHEMORADIOTHERAPY USING INTRARECTAL 5-FLUORURACIL IN COMBINED TREATMENT OF RECTAL CANCER

Abstract

Safety and efficacy of intrarectal 5-fluoruracil in combined treatment of localized rectal cancer was investigated in this article. Our data supports safety, economical efficacy and simplicity of use of this method. It improves sphincter preservation rate in patients with distal rectal cancer, does not increase surgical mortality and morbidity, leads to high tumor regression rate, improves local control and decreases distant failure rate.

Keywords

• rectal cancer
• combined treatment
• 5-fluoruracil
• capecitabine
• tegafur