Communications Biology (Nov 2022)
Proteogenomic landscape and clinical characterization of GH-producing pituitary adenomas/somatotroph pituitary neuroendocrine tumors
- Azusa Yamato,
- Hidekazu Nagano,
- Yue Gao,
- Tatsuma Matsuda,
- Naoko Hashimoto,
- Akitoshi Nakayama,
- Kazuyuki Yamagata,
- Masataka Yokoyama,
- Yingbo Gong,
- Xiaoyan Shi,
- Siti Nurul Zhahara,
- Takashi Kono,
- Yuki Taki,
- Naoto Furuki,
- Motoi Nishimura,
- Kentaro Horiguchi,
- Yasuo Iwadate,
- Masaki Fukuyo,
- Bahityar Rahmutulla,
- Atsushi Kaneda,
- Yoshinori Hasegawa,
- Yusuke Kawashima,
- Osamu Ohara,
- Tetsuo Ishikawa,
- Eiryo Kawakami,
- Yasuhiro Nakamura,
- Naoko Inoshita,
- Shozo Yamada,
- Noriaki Fukuhara,
- Hiroshi Nishioka,
- Tomoaki Tanaka
Affiliations
- Azusa Yamato
- Department of Molecular Diagnosis, Graduate School of Medicine, Chiba University
- Hidekazu Nagano
- Department of Molecular Diagnosis, Graduate School of Medicine, Chiba University
- Yue Gao
- Department of Molecular Diagnosis, Graduate School of Medicine, Chiba University
- Tatsuma Matsuda
- Department of Molecular Diagnosis, Graduate School of Medicine, Chiba University
- Naoko Hashimoto
- Department of Molecular Diagnosis, Graduate School of Medicine, Chiba University
- Akitoshi Nakayama
- Department of Molecular Diagnosis, Graduate School of Medicine, Chiba University
- Kazuyuki Yamagata
- Department of Molecular Diagnosis, Graduate School of Medicine, Chiba University
- Masataka Yokoyama
- Department of Molecular Diagnosis, Graduate School of Medicine, Chiba University
- Yingbo Gong
- Department of Molecular Diagnosis, Graduate School of Medicine, Chiba University
- Xiaoyan Shi
- Department of Molecular Diagnosis, Graduate School of Medicine, Chiba University
- Siti Nurul Zhahara
- Department of Molecular Diagnosis, Graduate School of Medicine, Chiba University
- Takashi Kono
- Department of Molecular Diagnosis, Graduate School of Medicine, Chiba University
- Yuki Taki
- Department of Molecular Diagnosis, Graduate School of Medicine, Chiba University
- Naoto Furuki
- Department of Molecular Diagnosis, Graduate School of Medicine, Chiba University
- Motoi Nishimura
- Division of Laboratory Medicine, Chiba University Hospital
- Kentaro Horiguchi
- Department of Neurological Surgery, Chiba University Hospital
- Yasuo Iwadate
- Department of Neurological Surgery, Chiba University Hospital
- Masaki Fukuyo
- Department of Molecular Oncology, Graduate School of Medicine, Chiba University
- Bahityar Rahmutulla
- Department of Molecular Oncology, Graduate School of Medicine, Chiba University
- Atsushi Kaneda
- Department of Molecular Oncology, Graduate School of Medicine, Chiba University
- Yoshinori Hasegawa
- Department of Applied Genomics, Kazusa DNA Research Institute
- Yusuke Kawashima
- Department of Applied Genomics, Kazusa DNA Research Institute
- Osamu Ohara
- Department of Applied Genomics, Kazusa DNA Research Institute
- Tetsuo Ishikawa
- Advanced Data Science Project, RIKEN Information R&D and Strategy Headquarters, RIKEN
- Eiryo Kawakami
- Advanced Data Science Project, RIKEN Information R&D and Strategy Headquarters, RIKEN
- Yasuhiro Nakamura
- Division of Pathology, Faculty of Medicine, Tohoku Medical and Pharmaceutical University
- Naoko Inoshita
- Department of Pathology, Moriyama Memorial Hospital
- Shozo Yamada
- Hypothalamic and Pituitary Center, Moriyama Neurological Center Hospital
- Noriaki Fukuhara
- Department of Hypothalamic and Pituitary Surgery, Toranomon Hospital
- Hiroshi Nishioka
- Department of Hypothalamic and Pituitary Surgery, Toranomon Hospital
- Tomoaki Tanaka
- Department of Molecular Diagnosis, Graduate School of Medicine, Chiba University
- DOI
- https://doi.org/10.1038/s42003-022-04272-1
- Journal volume & issue
-
Vol. 5,
no. 1
pp. 1 – 14
Abstract
The genetic alterations, protein expressions, and clinical characteristics of growth hormone-producing pituitary adenomas/somatotroph pituitary neuroendocrine tumors are integrated to detect molecules associated with acromegaly characteristics.
