Magnesium-based bioceramic-enhanced composites fabricated via friction stir processing

Matthew S. Dargusch; Nan Yang; Nagasivamuni Balasubramani; Jeffrey Venezuela; Shiyang Liu; Lei Jing; Yu Sen; Jiangtao Qu; Gui Wang; Julie Cairney

Smart Materials in Medicine (Sep 2024)

Magnesium-based bioceramic-enhanced composites fabricated via friction stir processing

Matthew S. Dargusch,
Nan Yang,
Nagasivamuni Balasubramani,
Jeffrey Venezuela,
Shiyang Liu,
Lei Jing,
Yu Sen,
Jiangtao Qu,
Gui Wang,
Julie Cairney

Affiliations

Matthew S. Dargusch: Centre for Advanced Materials Processing and Manufacturing (AMPAM), School of Mechanical and Mining Engineering, The University of Queensland, Brisbane, QLD, 4072, Australia; Corresponding author.
Nan Yang: Centre for Advanced Materials Processing and Manufacturing (AMPAM), School of Mechanical and Mining Engineering, The University of Queensland, Brisbane, QLD, 4072, Australia
Nagasivamuni Balasubramani: Centre for Advanced Materials Processing and Manufacturing (AMPAM), School of Mechanical and Mining Engineering, The University of Queensland, Brisbane, QLD, 4072, Australia
Jeffrey Venezuela: Centre for Advanced Materials Processing and Manufacturing (AMPAM), School of Mechanical and Mining Engineering, The University of Queensland, Brisbane, QLD, 4072, Australia
Shiyang Liu: Centre for Advanced Materials Processing and Manufacturing (AMPAM), School of Mechanical and Mining Engineering, The University of Queensland, Brisbane, QLD, 4072, Australia
Lei Jing: Shaanxi Key Laboratory of Biomedical Metallic Materials, Northwest Institute for Non-ferrous Metal Research, Xi'an, 710016, PR China
Yu Sen: Shaanxi Key Laboratory of Biomedical Metallic Materials, Northwest Institute for Non-ferrous Metal Research, Xi'an, 710016, PR China
Jiangtao Qu: Australian Centre for Microscopy and Microanalysis, The University of Sydney, NSW, 2006, Australia
Gui Wang: Centre for Advanced Materials Processing and Manufacturing (AMPAM), School of Mechanical and Mining Engineering, The University of Queensland, Brisbane, QLD, 4072, Australia
Julie Cairney: Australian Centre for Microscopy and Microanalysis, The University of Sydney, NSW, 2006, Australia

Journal volume & issue: Vol. 5, no. 3
pp. 447 – 459

Abstract

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Improving the degradation performance and enhancing the biocompatibility are the main challenges of Mg-based biodegradable implants. In this study, a nano-hydroxyapatite-enhanced (nHA) Mg matrix composite was fabricated via friction stir processing and characterised, including microstructure, mechanical, in vitro degradation properties, and cytocompatibility. Hydroxyapatite is renowned for its superior bone compatibility, promoting healing responses and tissue growth. Friction stirring created a gradient grain structure in the alloy, with the stir zone exhibiting the highest grain refinement. The stir zone also contained most of the incorporated nHA and exhibited a strong texture with grains preferentially oriented along the [0001] direction. Immersion and polarisation experiments showed an increase in the FSPed WE43-nHA's corrosion resistance due to the refined microstructure. The treatment also caused a shift in the corrosion mode of the alloy from localized to uniform corrosion despite some localized corrosion associated with the nHA. Cytocompatibility tests in human osteoblast (HOB) cell lines indicated good biocompatibility in the Mg-nHA alloy, with cells exhibiting relatively healthy morphology and increased live cell count. Friction stir processing is a viable manufacturing option for creating Mg-based metal matrix composites with improved corrosion resistance and good biocompatibility.

Published in Smart Materials in Medicine

ISSN: 2590-1834 (Online)
Publisher: KeAi Communications Co., Ltd.
Country of publisher: China
LCC subjects: Technology
Website: https://www.keaipublishing.com/en/journals/smart-materials-in-medicine/

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