PLoS ONE (Jan 2022)

The correlation between serum albumin and diabetic retinopathy among people with type 2 diabetes mellitus: NHANES 2011-2020.

  • Gao-Xiang Wang,
  • Ze-Bin Fang,
  • Jun-Tong Li,
  • Bao-Li Huang,
  • De-Liang Liu,
  • Shu-Fang Chu,
  • Hui-Lin Li

DOI
https://doi.org/10.1371/journal.pone.0270019
Journal volume & issue
Vol. 17, no. 6
p. e0270019

Abstract

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ObjectivesThe objective of this research aimed to investigate the correlation involving serum albumin with diabetic retinopathy (DR) in patients with type 2 diabetes mellitus (T2DM).MethodsFrom 2011 to 2020, the National Health and Nutrition Examination Survey (NHANES) surveyed 45462 participants. We used the relevant data to conduct descriptive statistics, linear regression, and Logistic regression analysis.ResultsAfter adjusting for age, sex, and race, as well as all other variables, serum albumin was significantly negatively related to DR (P0.05).ConclusionAlbumin levels in the serum have a quantitatively significant negative correlation with DR. Serum albumin levels in the blood can be used as a reference point for protracted follow-up of people with T2DM.