A retrospective evaluation of therapeutic efficacy and safety of chemoradiotherapy in older patients (aged ≥ 75 years) with limited-disease small cell lung cancer: insights from two institutions and review of the literature

Shiono Ayako; Imai Hisao; Endo Satoshi; Katayama Kazuki; Sato Hideaki; Hashimoto Kosuke; Miura Yu; Okazaki Shohei; Abe Takanori; Mouri Atsuto; Kaira Kyoichi; Masubuchi Ken; Kobayashi Kunihiko; Minato Koichi; Kato Shingo; Kagamu Hiroshi

doi:10.2478/raon-2024-0054

Radiology and Oncology (Sep 2024)

A retrospective evaluation of therapeutic efficacy and safety of chemoradiotherapy in older patients (aged ≥ 75 years) with limited-disease small cell lung cancer: insights from two institutions and review of the literature

Shiono Ayako,
Imai Hisao,
Endo Satoshi,
Katayama Kazuki,
Sato Hideaki,
Hashimoto Kosuke,
Miura Yu,
Okazaki Shohei,
Abe Takanori,
Mouri Atsuto,
Kaira Kyoichi,
Masubuchi Ken,
Kobayashi Kunihiko,
Minato Koichi,
Kato Shingo,
Kagamu Hiroshi

Affiliations

Shiono Ayako: Department of Respiratory Medicine, International Medical Center, Saitama Medical University, Saitama, Japan
Imai Hisao: Department of Respiratory Medicine, International Medical Center, Saitama Medical University, Saitama, Japan
Endo Satoshi: Division of Respiratory Medicine, Gunma Prefectural Cancer Center, Gunma, Japan
Katayama Kazuki: Department of Respiratory Medicine, International Medical Center, Saitama Medical University, Saitama, Japan
Sato Hideaki: Department of Respiratory Medicine, International Medical Center, Saitama Medical University, Saitama, Japan
Hashimoto Kosuke: Department of Respiratory Medicine, International Medical Center, Saitama Medical University, Saitama, Japan
Miura Yu: Department of Respiratory Medicine, International Medical Center, Saitama Medical University, Saitama, Japan
Okazaki Shohei: Division of Radiation Oncology, Gunma Prefectural Cancer Center, Gunma, Japan
Abe Takanori: Department of Radiation Oncology, International Medical Center, Saitama Medical University, Saitama, Japan
Mouri Atsuto: Department of Respiratory Medicine, International Medical Center, Saitama Medical University, Saitama, Japan
Kaira Kyoichi: Department of Respiratory Medicine, International Medical Center, Saitama Medical University, Saitama, Japan
Masubuchi Ken: Division of Respiratory Medicine, Gunma Prefectural Cancer Center, Gunma, Japan
Kobayashi Kunihiko: Department of Respiratory Medicine, International Medical Center, Saitama Medical University, Saitama, Japan
Minato Koichi: Division of Respiratory Medicine, Gunma Prefectural Cancer Center, Gunma, Japan
Kato Shingo: Department of Radiation Oncology, International Medical Center, Saitama Medical University, Saitama, Japan
Kagamu Hiroshi: Department of Respiratory Medicine, International Medical Center, Saitama Medical University, Saitama, Japan

DOI: https://doi.org/10.2478/raon-2024-0054
Journal volume & issue: Vol. 58, no. 3
pp. 432 – 443

Abstract

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The standard treatment for patients in good general condition with limited-disease small cell lung cancer (LD-SCLC) is concurrent platinum/etoposide chemotherapy and thoracic radiotherapy (TRT). However, the efficacy and safety of chemoradiotherapy (CRT) in older patients with LD-SCLC has not been fully explored; moreover, the optimal treatment for this patient group remains unclear. This study aimed to investigate the feasibility and efficacy of CRT in older patients with LD-SCLC.

Published in Radiology and Oncology

ISSN: 1581-3207 (Online)
Publisher: Sciendo
Country of publisher: Slovenia
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://sciendo.com/journal/RAON

About the journal

Abstract

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