Mediators of Inflammation (Jan 2012)

Increased Expression of Visfatin in Monocytes and Macrophages in Male Acute Myocardial Infarction Patients

  • Cheng-An Chiu,
  • Teng-Hung Yu,
  • Wei-Chin Hung,
  • Li-Fen Lu,
  • Fu-Mei Chung,
  • I-Ting Tsai,
  • Chih-Ying Yang,
  • Chia-Chang Hsu,
  • Yung-Chuan Lu,
  • Jer-Yiing Houng,
  • Yau-Jiunn Lee,
  • Chao-Ping Wang

DOI
https://doi.org/10.1155/2012/469852
Journal volume & issue
Vol. 2012

Abstract

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We demonstrated that visfatin expressed in monocytes and neutrophils and increased their reactivity in male acute ST-segment elevation myocardial infarction patients. Furthermore, visfatin was strongly appeared in lipid rich coronary rupture plaques and macrophages. These results suggest another explanation about leukocytes mediated visfatin that may play a pathogenesis role in coronary vulnerable plaques rupture.