An Enantioselective Potentiometric Sensor for 2-Amino-1-Butanol Based on Chiral Porous Organic Cage CC3-R
Bang-Jin Wang,
Ai-Hong Duan,
Jun-Hui Zhang,
Sheng-Ming Xie,
Qiu-E Cao,
Li-Ming Yuan
Affiliations
Bang-Jin Wang
Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming 650091, China
Ai-Hong Duan
Department of Chemistry, Yunnan Normal University, Kunming 650500, China
Jun-Hui Zhang
Department of Chemistry, Yunnan Normal University, Kunming 650500, China
Sheng-Ming Xie
Department of Chemistry, Yunnan Normal University, Kunming 650500, China
Qiu-E Cao
Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming 650091, China
Li-Ming Yuan
Department of Chemistry, Yunnan Normal University, Kunming 650500, China
Porous organic cages (POCs) have attracted extensive attention due to their unique structures and tremendous application potential in numerous areas. In this study, an enantioselective potentiometric sensor composed of a polyvinyl chloride (PVC) membrane electrode modified with CC3-R POC material was used for the recognition of enantiomers of 2-amino-1-butanol. After optimisation, the developed sensor exhibited enantioselectivity toward S-2-amino-1-butanol ( log K S , R P o t = −0.98) with acceptable sensitivity, and a near-Nernstian response of 25.8 ± 0.3 mV/decade within a pH range of 6.0⁻9.0.
