Molecules
(Aug 2022)
A Convenient, Rapid, Conventional Heating Route to MIDA Boronates
Andrew McGown,
Anthony K. Edmonds,
Daniel Guest,
Verity L. Holmes,
Chris Dadswell,
Ramón González-Méndez,
Charles A. I. Goodall,
Mark C. Bagley,
Barnaby W. Greenland,
John Spencer
Affiliations
Andrew McGown
Department of Chemistry, School of Life Sciences, University of Sussex, Brighton BN1 9QJ, UK
Anthony K. Edmonds
Department of Chemistry, School of Life Sciences, University of Sussex, Brighton BN1 9QJ, UK
Daniel Guest
Department of Chemistry, School of Life Sciences, University of Sussex, Brighton BN1 9QJ, UK
Verity L. Holmes
Department of Chemistry, School of Life Sciences, University of Sussex, Brighton BN1 9QJ, UK
Chris Dadswell
Department of Chemistry, School of Life Sciences, University of Sussex, Brighton BN1 9QJ, UK
Ramón González-Méndez
Department of Chemistry, School of Life Sciences, University of Sussex, Brighton BN1 9QJ, UK
Charles A. I. Goodall
Faculty of Engineering & Science, University of Greenwich, Medway Campus, Central Avenue, Chatham Maritime, Chatham ME4 4TB, UK
Mark C. Bagley
Department of Chemistry, School of Life Sciences, University of Sussex, Brighton BN1 9QJ, UK
Barnaby W. Greenland
Department of Chemistry, School of Life Sciences, University of Sussex, Brighton BN1 9QJ, UK
John Spencer
Department of Chemistry, School of Life Sciences, University of Sussex, Brighton BN1 9QJ, UK
DOI
https://doi.org/10.3390/molecules27165052
Journal volume & issue
Vol. 27,
no. 16
Abstract
Read online
A cheap, conventional, sealed heating reactor proved to be a useful alternative to a microwave reactor in the synthesis of a >20-member MIDA boronate library (MIDA = N-methyliminodiacetic acid). Reaction times were 10 min and work-ups were minimal, saving on energy and solvent usage.
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