A Fluorescent Probe as a Lead Compound for a Selective α‑Synuclein PET Tracer: Development of a Library of 2‑Styrylbenzothiazoles and Biological Evaluation of [18F]PFSB and [18F]MFSB

• Adriana Di Nanni,
• Ran Sing Saw,
• Umberto M. Battisti,
• Gregory D. Bowden,
• Adam Boeckermann,
• Kaare Bjerregaard-Andersen,
• Bernd J. Pichler,
• Kristina Herfert,
• Matthias M. Herth,
• Andreas Maurer

Affiliations

Adriana Di Nanni

Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tübingen, Tübingen, Germany

Ran Sing Saw

Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tübingen, Tübingen, Germany

Umberto M. Battisti

Department of Drug Design and Pharmacology, Faculty of Health and Medicinal Sciences, University of Copenhagen, Copenhagen, Denmark

Gregory D. Bowden

Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tübingen, Tübingen, Germany

Adam Boeckermann

Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tübingen, Tübingen, Germany

Kaare Bjerregaard-Andersen

Department of Antibody Engineering and Biochemistry, Valby, Denmark

Bernd J. Pichler

Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tübingen, Tübingen, Germany

Kristina Herfert

Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tübingen, Tübingen, Germany

Matthias M. Herth

Department of Drug Design and Pharmacology, Faculty of Health and Medicinal Sciences, University of Copenhagen, Copenhagen, Denmark

Andreas Maurer

Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tübingen, Tübingen, Germany