Diagnostic and Interventional Radiology (May 2023)
Evaluation of abdominal computed tomography findings in patients with COVID-19: a multicenter study
- Mehmet Ruhi Onur,
- Yakup Özbay,
- İlkay İdilman,
- Ali Devrim Karaosmanoğlu,
- Selma Uysal Ramadan,
- Funda Barlık,
- Sonay Aydın,
- Hüseyin Odaman,
- Canan Altay,
- Işıl Başara Akın,
- Oğuz Dicle,
- Özgür Appak,
- Başak Gülpınar,
- Ayşe Erden,
- Sezer Kula,
- Ayşegül Gürsöy Çoruh,
- Diğdem Kuru Öz,
- Melahat Kul,
- Çağlar Uzun,
- Erdal Karavaş,
- Akın Levent,
- Hakan Artaş,
- Hasan Eryeşil,
- Onur Solmaz,
- Türkkan Öztürk Kaygusuz,
- Mustafa Faraşat,
- Ahmet Burak Kale,
- Fatih Düzgün,
- Gökhan Pekindil,
- F. Demir Apaydın,
- Meltem Nass Duce,
- Yüksel Balcı,
- Kaan Esen,
- Ayşegül Sağır Kahraman,
- Leyla Karaca,
- Zeynep Maraş Özdemir,
- Bayram Kahraman,
- Mesude Tosun,
- Mehmet Selim Nural,
- İlkay Çamlıdağ,
- Mustafa Arda Onar,
- Kaan Ballı,
- Ezgi Güler,
- Mustafa Harman,
- Nevra Zehra Elmas,
- Cansu Öztürk,
- Özlem Güngör,
- Duygu Herek,
- Ahmet Baki Yağcı,
- Cengiz Erol,
- Mehmet Şeker,
- İrem İşlek,
- Yusuf Can,
- Serdar Aslan,
- M. Yasemin Karadeniz Bilgili,
- Alper Göncüoğlu,
- Hatice Keleş,
- Pelin Zeynep Bekin Sarıkaya,
- Barış Bakır,
- Merve Gülbiz Dağoğlu Kartal,
- Görkem Durak,
- Gülşen Yücel Oğuzdoğan,
- Fatih Alper,
- Ahmet Yalçın,
- Safiye Gürel,
- Bircan Alan,
- Elif Gündoğdu,
- Nevin Aydın,
- Ayşegül Cansu,
- Ceyda Civan Kuş,
- Elif Ofluoğlu Tuncer,
- Ferhat Can Pişkin,
- Hale Çolakoğlu Er,
- Bumin Değirmenci,
- Mustafa Nasuh Özmen,
- Mecit Kantarcı,
- Muşturay Karçaaltıncaba
Affiliations
- Mehmet Ruhi Onur
- Department of Radiology, Hacettepe University Faculty of Medicine, Ankara, Turkey
- Yakup Özbay
- Department of Radiology, Hacettepe University Faculty of Medicine, Ankara, Turkey
- İlkay İdilman
- Department of Radiology, Hacettepe University Faculty of Medicine, Ankara, Turkey
- Ali Devrim Karaosmanoğlu
- Department of Radiology, Hacettepe University Faculty of Medicine, Ankara, Turkey
- Selma Uysal Ramadan
- Clinic of Radiology, University of Health Sciences Turkey, Ankara Atatürk Sanatorium Training and Research Hospital, Ankara, Turkey
- Funda Barlık
- Department of Radiology, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey
- Sonay Aydın
- Department of Radiology, Binali Yıldırım University Faculty of Medicine, Erzincan, Turkey
- Hüseyin Odaman
- Department of Radiology, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey
- Canan Altay
- Department of Radiology, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey
- Işıl Başara Akın
- Department of Radiology, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey
- Oğuz Dicle
- Department of Radiology, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey
- Özgür Appak
- Department of Medical Microbiology, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey
- Başak Gülpınar
- Department of Radiology, Ankara University Faculty of Medicine, Ankara, Turkey
- Ayşe Erden
- Department of Radiology, Ankara University Faculty of Medicine, Ankara, Turkey
- Sezer Kula
- Department of Radiology, Ankara University Faculty of Medicine, Ankara, Turkey
- Ayşegül Gürsöy Çoruh
- Department of Radiology, Ankara University Faculty of Medicine, Ankara, Turkey
- Diğdem Kuru Öz
- Department of Radiology, Ankara University Faculty of Medicine, Ankara, Turkey
- Melahat Kul
- Department of Radiology, Ankara University Faculty of Medicine, Ankara, Turkey
- Çağlar Uzun
- Department of Radiology, Ankara University Faculty of Medicine, Ankara, Turkey
- Erdal Karavaş
- Department of Radiology, Binali Yıldırım University Faculty of Medicine, Erzincan, Turkey
- Akın Levent
- Department of Radiology, Binali Yıldırım University Faculty of Medicine, Erzincan, Turkey
- Hakan Artaş
- Department of Radiology, Fırat University Faculty of Medicine, Elazığ, Turkey
- Hasan Eryeşil
- Department of Radiology, Fırat University Faculty of Medicine, Elazığ, Turkey
- Onur Solmaz
- Department of Radiology, Fırat University Faculty of Medicine, Elazığ, Turkey
- Türkkan Öztürk Kaygusuz
- Department of Infectious Diseases and Clinical Microbiology, Fırat University Faculty of Medicine, Elazığ, Turkey
- Mustafa Faraşat
- Department of Radiology, Celal Bayar University Faculty of Medicine, Manisa, Turkey
- Ahmet Burak Kale
- Department of Radiology, Celal Bayar University Faculty of Medicine, Manisa, Turkey
- Fatih Düzgün
- Department of Radiology, Celal Bayar University Faculty of Medicine, Manisa, Turkey
- Gökhan Pekindil
- Department of Radiology, Celal Bayar University Faculty of Medicine, Manisa, Turkey
- F. Demir Apaydın
- Department of Radiology, Mersin University Faculty of Medicine, Mersin, Turkey
- Meltem Nass Duce
- Department of Radiology, Mersin University Faculty of Medicine, Mersin, Turkey
- Yüksel Balcı
- Department of Radiology, Mersin University Faculty of Medicine, Mersin, Turkey
- Kaan Esen
- Department of Radiology, Mersin University Faculty of Medicine, Mersin, Turkey
- Ayşegül Sağır Kahraman
- Department of Radiology, İnönü University Faculty of Medicine, Malatya, Turkey
- Leyla Karaca
- Department of Radiology, İnönü University Faculty of Medicine, Malatya, Turkey
- Zeynep Maraş Özdemir
- Department of Radiology, İnönü University Faculty of Medicine, Malatya, Turkey
- Bayram Kahraman
- Clinic of Radiology, Specialist Doctor Bayram Kahraman Radiology Clinic, Malatya, Turkey
- Mesude Tosun
- Department of Radiology, Kocaeli University Faculty of Medicine, Kocaeli, Turkey
- Mehmet Selim Nural
- Department of Radiology, Ondokuz Mayıs University Faculty of Medicine, Samsun, Turkey
- İlkay Çamlıdağ
- Department of Radiology, Ondokuz Mayıs University Faculty of Medicine, Samsun, Turkey
- Mustafa Arda Onar
- Department of Radiology, Ondokuz Mayıs University Faculty of Medicine, Samsun, Turkey
- Kaan Ballı
- Department of Radiology, Ege University Faculty of Medicine, İzmir, Turkey
- Ezgi Güler
- Department of Radiology, Ege University Faculty of Medicine, İzmir, Turkey
- Mustafa Harman
- Department of Radiology, Ege University Faculty of Medicine, İzmir, Turkey
- Nevra Zehra Elmas
- Department of Radiology, Ege University Faculty of Medicine, İzmir, Turkey
- Cansu Öztürk
- Clinic of Radiology, University of Health Sciences Turkey, Ankara Atatürk Sanatorium Training and Research Hospital, Ankara, Turkey
- Özlem Güngör
- Clinic of Radiology, University of Health Sciences Turkey, Ankara Atatürk Sanatorium Training and Research Hospital, Ankara, Turkey
- Duygu Herek
- Department of Radiology, Pamukkale University Faculty of Medicine, Denizli, Turkey
- Ahmet Baki Yağcı
- Department of Radiology, Pamukkale University Faculty of Medicine, Denizli, Turkey
- Cengiz Erol
- Department of Radiology, Medipol University Faculty of Medicine, İstanbul, Turkey
- Mehmet Şeker
- Department of Radiology, Medipol University Faculty of Medicine, İstanbul, Turkey
- İrem İşlek
- Department of Radiology, Medipol University Faculty of Medicine, İstanbul, Turkey
- Yusuf Can
- Department of Radiology, Medipol University Faculty of Medicine, İstanbul, Turkey
- Serdar Aslan
- Department of Radiology, Giresun University Faculty of Medicine, Giresun, Turkey
- M. Yasemin Karadeniz Bilgili
- Department of Radiology, Lokman Hekim University Faculty of Medicine, Ankara, Turkey
- Alper Göncüoğlu
- Department of Radiology, Kırıkkale University Faculty of Medicine, Kırıkkale, Turkey
- Hatice Keleş
- Department of Internal Medicine, Kırıkkale University Faculty of Medicine, Kırıkkale, Turkey
- Pelin Zeynep Bekin Sarıkaya
- Department of Radiology, Kırıkkale University Faculty of Medicine, Kırıkkale, Turkey
- Barış Bakır
- Department of Radiology, İstanbul University, İstanbul Faculty of Medicine, İstanbul, Turkey
- Merve Gülbiz Dağoğlu Kartal
- Department of Radiology, İstanbul University, İstanbul Faculty of Medicine, İstanbul, Turkey
- Görkem Durak
- Department of Radiology, İstanbul University, İstanbul Faculty of Medicine, İstanbul, Turkey
- Gülşen Yücel Oğuzdoğan
- Clinic of Radiology, University of Health Sciences Turkey, Başakşehir Çam and Sakura City Hospital, İstanbul, Turkey
- Fatih Alper
- Department of Radiology, Atatürk University Faculty of Medicine, Erzurum, Turkey
- Ahmet Yalçın
- Department of Radiology, Atatürk University Faculty of Medicine, Erzurum, Turkey
- Safiye Gürel
- Department of Radiology, Bolu Abant İzzet Baysal University Faculty of Medicine, Bolu, Turkey
- Bircan Alan
- Department of Radiology, Bolu Abant İzzet Baysal University Faculty of Medicine, Bolu, Turkey
- Elif Gündoğdu
- Department of Radiology, Eskişehir Osmangazi University Faculty of Medicine, Eskişehir, Turkey
- Nevin Aydın
- Department of Radiology, Eskişehir Osmangazi University Faculty of Medicine, Eskişehir, Turkey
- Ayşegül Cansu
- Department of Radiology, Karadeniz Technical University Faculty of Medicine, Trabzon, Turkey
- Ceyda Civan Kuş
- Clinic of Radiology, Marmara University Training and Research Hospital, İstanbul, Turkey
- Elif Ofluoğlu Tuncer
- Clinic of Radiology, University of Health Sciences Turkey, Sultan 2. Abdulhamid Han Training and Research Hospital, İstanbul, Turkey
- Ferhat Can Pişkin
- Department of Radiology, Çukurova University Faculty of Medicine, Adana, Turkey
- Hale Çolakoğlu Er
- Department of Radiology, Ufuk University Faculty of Medicine, Ankara, Turkey
- Bumin Değirmenci
- Clinic of Radiology, Antalya ASV Life Hospital, Antalya, Turkey
- Mustafa Nasuh Özmen
- Department of Radiology, Hacettepe University Faculty of Medicine, Ankara, Turkey
- Mecit Kantarcı
- Department of Radiology, Binali Yıldırım University Faculty of Medicine, Erzincan, Turkey
- Muşturay Karçaaltıncaba
- Department of Radiology, Hacettepe University Faculty of Medicine, Ankara, Turkey
- DOI
- https://doi.org/10.4274/dir.2022.221575
- Journal volume & issue
-
Vol. 29,
no. 3
pp. 414 – 427
Abstract
PURPOSETo evaluate the frequency of abdominal computed tomography (CT) findings in patients with coronavirus disease-2019 (COVID-19) and interrogate the relationship between abdominal CT findings and patient demographic features, clinical findings, and laboratory test results as well as the CT atherosclerosis score in the abdominal aorta.METHODSThis study was designed as a multicenter retrospective study. The abdominal CT findings of 1.181 patients with positive abdominal symptoms from 26 tertiary medical centers with a positive polymerase chain-reaction test for severe acute respiratory syndrome coronavirus 2 were reviewed. The frequency of ischemic and non-ischemic CT findings as well as the association between CT findings, clinical features, and abdominal aortic calcific atherosclerosis score (AA-CAS) were recorded.RESULTSIschemic and non-ischemic abdominal CT findings were detected in 240 (20.3%) and 328 (27.7%) patients, respectively. In 147 patients (12.4%), intra-abdominal malignancy was present. The most frequent ischemic abdominal CT findings were bowel wall thickening (n = 120; 10.2%) and perivascular infiltration (n = 40; 3.4%). As for non-ischemic findings, colitis (n = 91; 7.7%) and small bowel inflammation (n = 73; 6.2%) constituted the most frequent disease processes. The duration of hospital stay was found to be higher in patients with abdominal CT findings than in patients without any positive findings (13.8 ± 13 vs. 10.4 ± 12.8 days, P < 0.001). The frequency of abdominal CT findings was significantly higher in patients who did not survive the infection than in patients who were discharged after recovery (41.7% vs. 27.4%, P < 0.001). Increased AA-CAS was found to be associated with a higher risk of ischemic conditions in abdominal CT examinations.CONCLUSIONAbdominal symptoms in patients with COVID-19 are usually associated with positive CT findings. The presence of ischemic findings on CT correlates with poor COVID-19 outcomes. A high AA-CAS is associated with abdominal ischemic findings in patients with COVID-19.
Keywords