Nano TiO2 photocatalytic combined with optimized operating room care in postoperative infection after gynecological open abdominal surgery

Abstract

Background: Disinfection of the operating room environment is essential to reduce the incidence of infection after laparotomy in obstetrics and gynecology. With the development of science and technology, nano-titanium dioxide (TiO2) photocatalytic technology has attracted much attention due to its high efficiency and low cost. To explore the effect of TiO2 photocatalytic technology and optimized operating room care in the prevention of postoperative infection in obstetrics and gynecology department. Methods: Nano-TiO2 photocatalysts were prepared and characterized, and their bactericidal effect was analyzed. A total of 96 patients with gynecological open abdominal surgery were randomly divided into control group (CG) and observation group (BG), 48 cases in each group. The CG received routine care and the BG received optimized care. The wound healing rate, infection rate, serum immunoglobulin, and inflammatory factor levels were compared. Results: The specific surface area of the nano-TiO2 photocatalyst was 75.1 m2/g, and the particle size was 16.6 nm, with rutile crystal structure. Compared with ultraviolet light, nano-TiO2 photocatalyst had better disinfection effect. Compared with the CG, the wound healing rate and IgG level were higher, and the infection rate, C-reactive protein, interleukin-6, and tumor necrosis factor-α were lower in the BG (P < 0.05). Conclusion: The combination of nano-TiO2 photocatalytic disinfection and optimized nursing care resulted in a 16.66 % reduction in postoperative infections and a 14.58 % improvement in wound healing. This is associated with lower airborne pathogens (66.6 CFU/m3) and improved immune-inflammatory markers (↑IgG, ↓CRP/IL-6/TNF-α).

Keywords

• Titanium dioxide
• Photocatalysis
• Air disinfection
• Open abdominal surgery
• Incision infection
• Optimized operating room care