Evaluation of Avian Reovirus S1133 Vaccine Strain in Neonatal Broiler Chickens in Gastrointestinal Integrity and Performance in a Large-Scale Commercial Field Trial
Victor Manuel Petrone-Garcia,
Joshua Gonzalez-Soto,
Raquel Lopez-Arellano,
Mariano Delgadillo-Gonzalez,
Victor M. Valdes-Narvaez,
Fernando Alba-Hurtado,
Xochitl Hernandez-Velasco,
Inkar Castellanos-Huerta,
Guillermo Tellez-Isaias
Affiliations
Victor Manuel Petrone-Garcia
Programa de Doctorado en Ciencias de la Salud y Producción Animal, Facultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de Mexico, Cuautitlán Izcalli 54714, Mexico
Joshua Gonzalez-Soto
Departamento de Ciencias Biológicas, Facultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de Mexico, Cuautitlán Izcalli 54714, Mexico
Raquel Lopez-Arellano
Laboratorio No 5: LEDEFAR, Unidad de Investigacion Multidisciplinaria, Facultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de Mexico, Cuautitlán Izcalli 54714, Mexico
Departamento de Ciencias Biológicas, Facultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de Mexico, Cuautitlán Izcalli 54714, Mexico
Xochitl Hernandez-Velasco
Departamento de Medicina y Zootecnia de Aves, Facultad de Medicina Veterinaria y Zootecnia, UNAM, Coyoacan 04510, Mexico
Inkar Castellanos-Huerta
Programa de Doctorado en Ciencias de la Salud y Producción Animal, Facultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de Mexico, Cuautitlán Izcalli 54714, Mexico
Guillermo Tellez-Isaias
Department of Poultry Science, University of Arkansas, Fayetteville, NC 72701, USA
Avian reovirus (ARV) is the principal cause of several diseases. The vaccination of breeders allows for the control of viral arthritis and delivery of maternal-derived antibodies to the progeny. The vaccination of broiler chickens with ARV strain S1133 is used to prevent viral arthritis. However, the post-vaccination enteric effects have not been well-characterized. The purpose of this study was to evaluate the effect of vaccination with the S1133 strain on the weight gain and feed conversion of broiler chickens and to characterize the gastric, enteric, and pancreatic lesions that the strain could induce. A total of 672,000 chickens were divided into two groups: a group vaccinated with ARV strain S1133 (S1133ARV) and a control group (not vaccinated). Upon histological analysis, the vaccine group showed less proventricular glandular tissue and atrophy of the pancreas and duodenal villi, as well as having a lower average daily profit. The conclusion based on the results of this investigation is that neonatal vaccination with S1133ARV causes atrophy of the pancreatic acini, proventricular glands, and intestinal villi, leading to an increased diameter of the glandular lumen and atrophy of the enteric villous, as well as weight loss, in broiler chickens.
