Nature Communications (Sep 2020)

An investigation of causal relationships between prediabetes and vascular complications

  • Pascal M. Mutie,
  • Hugo Pomares-Millan,
  • Naeimeh Atabaki-Pasdar,
  • Nina Jordan,
  • Rachel Adams,
  • Nicole L. Daly,
  • Juan Fernandes Tajes,
  • Giuseppe N. Giordano,
  • Paul W. Franks

DOI
https://doi.org/10.1038/s41467-020-18386-9
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 11

Abstract

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Prediabetes has been associated with diabetes complications, but these relationships may be confounded. Here the authors show, using genetic data in causal inference analyses, that prediabetes raises risk of coronary heart disease, but not other diabetes complications.