<i>Ascophyllum nodosum</i> (Linnaeus) Le Jolis from Arctic: Its Biochemical Composition, Antiradical Potential, and Human Health Risk
Ekaterina D. Obluchinskaya,
Olga N. Pozharitskaya,
Elena V. Gorshenina,
Anna V. Daurtseva,
Elena V. Flisyuk,
Yuliya E. Generalova,
Inna I. Terninko,
Alexander N. Shikov
Affiliations
Ekaterina D. Obluchinskaya
Murmansk Marine Biological Institute of the Russian Academy of Sciences (MMBI RAS), 17 Vladimirskaya Str., 183038 Murmansk, Russia
Olga N. Pozharitskaya
Murmansk Marine Biological Institute of the Russian Academy of Sciences (MMBI RAS), 17 Vladimirskaya Str., 183038 Murmansk, Russia
Elena V. Gorshenina
Murmansk Marine Biological Institute of the Russian Academy of Sciences (MMBI RAS), 17 Vladimirskaya Str., 183038 Murmansk, Russia
Anna V. Daurtseva
Murmansk Marine Biological Institute of the Russian Academy of Sciences (MMBI RAS), 17 Vladimirskaya Str., 183038 Murmansk, Russia
Elena V. Flisyuk
Department of Technology of Pharmaceutical Formulations, St. Petersburg State Chemical Pharmaceutical University, 14 Prof. Popov Str., 197376 Saint-Petersburg, Russia
Yuliya E. Generalova
Core Shared Research Facilities “Analytical Center”, St. Petersburg State Chemical Pharmaceutical University, 14 Prof. Popov Str., 197376 Saint-Petersburg, Russia
Inna I. Terninko
Core Shared Research Facilities “Analytical Center”, St. Petersburg State Chemical Pharmaceutical University, 14 Prof. Popov Str., 197376 Saint-Petersburg, Russia
Alexander N. Shikov
Murmansk Marine Biological Institute of the Russian Academy of Sciences (MMBI RAS), 17 Vladimirskaya Str., 183038 Murmansk, Russia
Ascophyllum nodosum is a brown seaweed common in Arctic tidal waters. We have collected A. nodosum samples from the Barents Sea (BS), Irminger Sea (IS), and Norwegian Sea (NS) in different reproductive stages and have evaluated their biochemical composition, radical scavenging potential, and health risks. The total content of dominating carbohydrates (fucoidan, mannitol, alginate, and laminaran) ranged from 347 mg/g DW in NS to 528 mg/g DW in BS. The proportion of two main structural monosaccharides of fucoidan (fucose and xylose) differed significantly between the seas and reproductive phase, reaching a maximum at the fertile phase in the BS sample. Polyphenols and flavonoids totals were highest in NS A. nodosum samples and increased on average in the following order: BS A. nodosum from the Arctic seas region was in the following order: Ca > Mg > Sr > Fe > Al > Zn > As total > Rb > Mn > Ba > Cu > Co. Seaweeds from BS had the lowest metal pollution index (MPI) of 38.4. A. nodosum from IS had the highest MPI of 83. According to the calculated target hazard quotient (THQ) and hazard index (HI) values, Arctic A. nodosum samples pose no carcinogenic risk to adult and child health and are safe for regular consumption. Our results suggest that the Arctic A. nodosum has a remarkable potential for food and pharmaceutical industries as an underestimated source of polysaccharides, polyphenols, and flavonoids.
