Segmental motor recovery after cervical spinal cord injury relates to density and integrity of corticospinal tract projections

Gustavo Balbinot; Guijin Li; Sukhvinder Kalsi-Ryan; Rainer Abel; Doris Maier; Yorck-Bernhard Kalke; Norbert Weidner; Rüdiger Rupp; Martin Schubert; Armin Curt; Jose Zariffa

doi:10.1038/s41467-023-36390-7

Nature Communications (Feb 2023)

Segmental motor recovery after cervical spinal cord injury relates to density and integrity of corticospinal tract projections

Gustavo Balbinot,
Guijin Li,
Sukhvinder Kalsi-Ryan,
Rainer Abel,
Doris Maier,
Yorck-Bernhard Kalke,
Norbert Weidner,
Rüdiger Rupp,
Martin Schubert,
Armin Curt,
Jose Zariffa

Affiliations

Gustavo Balbinot: KITE, Toronto Rehabilitation Institute, University Health Network
Guijin Li: KITE, Toronto Rehabilitation Institute, University Health Network
Sukhvinder Kalsi-Ryan: KITE, Toronto Rehabilitation Institute, University Health Network
Rainer Abel: Hohe Warte Bayreuth
Doris Maier: BG-Trauma Center
Yorck-Bernhard Kalke: RKU Universitäts- und Rehabilitationskliniken Ulm
Norbert Weidner: Spinal Cord Injury Center, Heidelberg University Hospital
Rüdiger Rupp: Spinal Cord Injury Center, Heidelberg University Hospital
Martin Schubert: Spinal Cord Injury Center, Balgrist University Hospital
Armin Curt: Spinal Cord Injury Center, Balgrist University Hospital
Jose Zariffa: KITE, Toronto Rehabilitation Institute, University Health Network

DOI: https://doi.org/10.1038/s41467-023-36390-7
Journal volume & issue: Vol. 14, no. 1
pp. 1 – 16

Abstract

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How the segmental innervation of upper limb muscles recovers after spinal cord injury is not fully understood. Here the authors show associations between corticospinal tract sparing and upper extremity recovery in spinal cord injury.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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