Nature Communications (Oct 2022)

Post-acute sequelae of SARS-CoV-2 with clinical condition definitions and comparison in a matched cohort

  • Michael A. Horberg,
  • Eric Watson,
  • Mamta Bhatia,
  • Celeena Jefferson,
  • Julia M. Certa,
  • Seohyun Kim,
  • Lily Fathi,
  • Keri N. Althoff,
  • Carolyn Williams,
  • Richard Moore

DOI
https://doi.org/10.1038/s41467-022-33573-6
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 13

Abstract

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In this study, the authors use electronic health record data from the US to characterise post-acute sequelae of SARS-CoV-2 infection (PASC). They identify 17 common PASC conditions and find an overall ~12% increase in risk of PASC conditions in the post-acute period among people with a SARS-CoV-2 positive test compared to matched test-negative controls.