Антибиотики и Химиотерапия (May 2020)

In vitro Efficacy of Ingavirin Against the Mexican Pandemic Subtype H1N1 of Influenza A Virus, Strains A/California/04/2009 and A/California/07/2009

  • S. YA. Loginova,
  • S. V. Borisevich,
  • M. V. Lykov,
  • E. V. Vedenina,
  • G. V. Borisevich,
  • V. P. Bondarev,
  • V. E. Nebolsin,
  • A. G. Chuchalin

Journal volume & issue
Vol. 54, no. 3-4
pp. 15 – 17

Abstract

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Ingavirin® was shown to be efficient in inhibition of the influenza virus strains A/California/04/2009 and A/California/07/2009 (H1N1) in the MDCK cell culture. The coefficient of the cytopathic activity inhibition amounted to 50 and 60%, and the inhibition coefficients of the specific hemagglutinin formation were 50 and 50%, and 79,1 and 75% before and after the enrichment in chick embryos respectively.

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