Robust and adjustable dynamic scattering compensation for high-precision deep tissue optogenetics

Zhenghan Li; Yameng Zheng; Xintong Diao; Rongrong Li; Ning Sun; Yongxian Xu; Xiaoming Li; Shumin Duan; Wei Gong; Ke Si

doi:10.1038/s42003-023-04487-w

Communications Biology (Jan 2023)

Robust and adjustable dynamic scattering compensation for high-precision deep tissue optogenetics

Zhenghan Li,
Yameng Zheng,
Xintong Diao,
Rongrong Li,
Ning Sun,
Yongxian Xu,
Xiaoming Li,
Shumin Duan,
Wei Gong,
Ke Si

Affiliations

Zhenghan Li: State Key Laboratory of Modern Optical Instrumentation, Department of Psychiatry of the First Affiliated Hospital, Zhejiang University School of Medicine
Yameng Zheng: Liangzhu Laboratory, MOE Frontier Science Center for Brain Science and Brain-machine Integration, State Key Laboratory of Brain-machine Intelligence, Zhejiang University
Xintong Diao: Liangzhu Laboratory, MOE Frontier Science Center for Brain Science and Brain-machine Integration, State Key Laboratory of Brain-machine Intelligence, Zhejiang University
Rongrong Li: Liangzhu Laboratory, MOE Frontier Science Center for Brain Science and Brain-machine Integration, State Key Laboratory of Brain-machine Intelligence, Zhejiang University
Ning Sun: Liangzhu Laboratory, MOE Frontier Science Center for Brain Science and Brain-machine Integration, State Key Laboratory of Brain-machine Intelligence, Zhejiang University
Yongxian Xu: Liangzhu Laboratory, MOE Frontier Science Center for Brain Science and Brain-machine Integration, State Key Laboratory of Brain-machine Intelligence, Zhejiang University
Xiaoming Li: Liangzhu Laboratory, MOE Frontier Science Center for Brain Science and Brain-machine Integration, State Key Laboratory of Brain-machine Intelligence, Zhejiang University
Shumin Duan: Liangzhu Laboratory, MOE Frontier Science Center for Brain Science and Brain-machine Integration, State Key Laboratory of Brain-machine Intelligence, Zhejiang University
Wei Gong: Liangzhu Laboratory, MOE Frontier Science Center for Brain Science and Brain-machine Integration, State Key Laboratory of Brain-machine Intelligence, Zhejiang University
Ke Si: State Key Laboratory of Modern Optical Instrumentation, Department of Psychiatry of the First Affiliated Hospital, Zhejiang University School of Medicine

DOI: https://doi.org/10.1038/s42003-023-04487-w
Journal volume & issue: Vol. 6, no. 1
pp. 1 – 12

Abstract

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A fast multidither coherent optical adaptive technology (fCOAT) focuses light through scattering tissue for optogenetic stimulation with subcellular resolution.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

About the journal