Emerging Infectious Diseases (Jun 2025)

Avian Influenza A(H5N1) Isolated from Dairy Farm Worker, Michigan, USA

  • Nicole Brock,
  • Joanna A. Pulit-Penaloza,
  • Jessica A. Belser,
  • Claudia Pappas,
  • Xiangjie Sun,
  • Troy J. Kieran,
  • Hui Zeng,
  • Juan A. De La Cruz,
  • Yasuko Hatta,
  • Han Di,
  • C. Todd Davis,
  • Terrence M. Tumpey,
  • Taronna R. Maines

DOI
https://doi.org/10.3201/eid3106.250386
Journal volume & issue
Vol. 31, no. 6
pp. 1253 – 1256

Abstract

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Influenza A(H5N1) viruses have been detected in US dairy cow herds since 2024. We assessed the pathogenesis, transmission, and airborne release of A/Michigan/90/2024, an H5N1 isolate from a dairy farm worker in Michigan, in the ferret model. Results show this virus caused airborne transmission with moderate pathogenicity, including limited extrapulmonary spread, without lethality.

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