Pathogens (May 2021)

First Autochthonous West Nile Lineage 2 and Usutu Virus Infections in Humans, July to October 2018, Czech Republic

  • Hana Zelená,
  • Jana Kleinerová,
  • Silvie Šikutová,
  • Petra Straková,
  • Hana Kocourková,
  • Roman Stebel,
  • Petr Husa,
  • Petr Husa,
  • Eva Tesařová,
  • Hana Lejdarová,
  • Oldřich Šebesta,
  • Peter Juráš,
  • Renata Ciupek,
  • Jakub Mrázek,
  • Ivo Rudolf

DOI
https://doi.org/10.3390/pathogens10060651
Journal volume & issue
Vol. 10, no. 6
p. 651

Abstract

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We present epidemiological, clinical and laboratory findings of five Czech patients diagnosed with autochthonous mosquito-borne disease—four patients with confirmed West Nile virus (WNV) and one patient with Usutu virus (USUV) infections, from July to October 2018, including one fatal case due to WNV. This is the first documented human outbreak caused by WNV lineage 2 in the Czech Republic and the first record of a neuroinvasive human disease caused by USUV, which illustrates the simultaneous circulation of WNV and USUV in the country.

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