Enhanced Carbapenem Resistance through Multimerization of Plasmids Carrying Carbapenemase Genes
Ryuichiro Abe,
Yukihiro Akeda,
Yo Sugawara,
Yuki Matsumoto,
Daisuke Motooka,
Ryuji Kawahara,
Norihisa Yamamoto,
Kazunori Tomono,
Tetsuya Iida,
Shigeyuki Hamada
Affiliations
Ryuichiro Abe
Japan-Thailand Research Collaboration Center on Emerging and Re-emerging Infections, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan
Japan-Thailand Research Collaboration Center on Emerging and Re-emerging Infections, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan
Japan-Thailand Research Collaboration Center on Emerging and Re-emerging Infections, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan
Yuki Matsumoto
Department of Infection Metagenomics, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan
Daisuke Motooka
Department of Infection Metagenomics, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan
Ryuji Kawahara
Department of Microbiology, Osaka Institute of Public Health, Osaka, Japan
Norihisa Yamamoto
Division of Infection Control and Prevention, Osaka University Hospital, Suita, Japan
Kazunori Tomono
Division of Infection Control and Prevention, Osaka University Hospital, Suita, Japan
Tetsuya Iida
Japan-Thailand Research Collaboration Center on Emerging and Re-emerging Infections, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan
Shigeyuki Hamada
Japan-Thailand Research Collaboration Center on Emerging and Re-emerging Infections, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan
We demonstrated the multimerization of plasmids harboring carbapenemase genes, and multimeric plasmids of various discrete sizes existed in a host bacterial cell of Escherichia coli
