Oman Medical Journal (May 2022)

Mixed Connective Tissue Disease with Severe Axonal Polyneuropathy: A Case Report

  • Talal Al Lawati,
  • Batool Hassan

DOI
https://doi.org/10.5001/omj.2022.08
Journal volume & issue
Vol. 37, no. 3
pp. e376 – e376

Abstract

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Mixed connective tissue disease (MCTD) is a unique disorder characterized by the presence of a high titer of anti-U1 ribonucloprotein antibody with overlapping features of various connective tissue disorders including systemic lupus erythematosus, scleroderma, and myositis. Severe renal or neurological involvement is unusual with this disorder. We describe a case of biopsy-confirmed severe sensorimotor axonal polyneuropathy in a middle-aged gentleman as his first presentation for MCTD.

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