Nature Communications (Aug 2022)

Scarf enables a highly memory-efficient analysis of large-scale single-cell genomics data

  • Parashar Dhapola,
  • Johan Rodhe,
  • Rasmus Olofzon,
  • Thomas Bonald,
  • Eva Erlandsson,
  • Shamit Soneji,
  • Göran Karlsson

DOI
https://doi.org/10.1038/s41467-022-32097-3
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 14

Abstract

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As the scale of single-cell genomics experiments grows into the millions, the computational requirements to process this data are beyond the reach of many. Here the authors present Scarf, a modularly designed Python package that makes the analysis workflow highly memory efficient such that even the largest existing datasets can be analyzed on an average modern laptop.