Viruses (Sep 2024)

Review of the Effects of Antiviral Therapy on Hepatitis B/C-Related Mortality and the Regression of Fibrosis

  • Stephen Sinclair,
  • Sean Shearen,
  • Youssef Ghobrial,
  • George Trad,
  • Syed Abdul Basit,
  • David Shih,
  • John K. Ryan

DOI
https://doi.org/10.3390/v16101531
Journal volume & issue
Vol. 16, no. 10
p. 1531

Abstract

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Hepatitis B and Hepatitis C are viral causes of Hepatitis that lead to significant worldwide mortality and morbidity through the sequelae of fibrosis and hepatocellular carcinoma. In this review, we have summarized recent studies that have examined the effects of antiviral therapy on the regression of fibrosis and the reduction in mortalities associated with the viruses. Antiviral therapy significantly decreases mortality and induces the regression of fibrosis.

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