Revista da Sociedade Brasileira de Medicina Tropical (Apr 2013)

Rotavirus G2P[4] and G2P[4]+[6] infections during norovirus gastroenteritis outbreak: summer season 2010, Brazil

  • Adriana Luchs,
  • Simone Guadagnucci Morillo,
  • Cibele Daniel Ribeiro,
  • Audrey Cilli,
  • Samira Julien Calux,
  • Rita de Cássia Compagnoli Carmona,
  • Maria do Carmo Sampaio Tavares Timenetsky

Journal volume & issue
Vol. 46, no. 2
pp. 227 – 230

Abstract

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Introduction This study aimed to monitor the seasonality of rotavirus infection, and gain insight into the variability of Brazilian strains. Methods A total of 28 stool samples were analyzed from 698 revised cases of gastroenteritis during a norovirus outbreak in the summer of 2010 in Guarujá, Brazil. Diagnosis was performed using enzyme-linked immunosorbent assay (ELISA), reverse transcription polymerase chain reaction (RT-PCR), and sequencing. Results Rotavirus infection was detected in 17.9% (5/28) of samples; 4 samples were G2P[4] genotype, and one G2P[4]+P[6] genotype. G2 and P[4] sequences showed a genetic relationship to strains from India and Russia, respectively. Conclusions The seasonal pattern of rotavirus may be a consequence of human activity apart from climate factors.

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