Clinical, Cosmetic and Investigational Dermatology (Jul 2022)

Case Report: Omalizumab Successfully Treated Recalcitrant Bullous Pemphigoid in an Elderly Patient with Multiple Comorbidities

  • Liu J,
  • Xiang T,
  • Wang W,
  • Bu Z

Journal volume & issue
Vol. Volume 15
pp. 1391 – 1396

Abstract

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Jue Liu,1 Tingkai Xiang,2 Wei Wang,3 Zhangyu Bu1 1Department of Dermatology, Affiliated Hangzhou First People’s Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of China; 2The Fourth School of Medicine Affiliated to Zhejiang Chinese Medical University, Hangzhou, People’s Republic of China; 3Department of Pathology, Affiliated Hangzhou First People’s Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of ChinaCorrespondence: Zhangyu Bu, Department of Dermatology, Affiliated Hangzhou First People’s Hospital, Zhejiang University School of Medicine, No. 261, Huansha Road, Hangzhou, People’s Republic of China, Tel/Fax +86 13868167009, Email [email protected]: Bullous pemphigoid (BP) is an autoimmune blistering disease mainly affecting elderly individuals. Comorbidities are common in patients with BP and have been found to complicate the management and prognosis. We describe a patient with multiple comorbidities who was successfully treated with omalizumab and suggest omalizumab as a good alternative therapy for BP to prevent treatment-related complications in elderly patients with a poor general condition.Keywords: bullous pemphigoid, comorbidities, omalizumab, elderly, case report

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